Everton are on a dreadful run of results but always seem able to raise their game when entertaining Merseyside rivals Liverpool. The last four Goodison Park derbies have ended in stalemate and these neighbours have shared the spoils eight times in nine meetings at this venue.
Manchester United have pulled off a couple of nice results since Ole Gunnar Solskjaer left but their performances remain unconvincing. The Red Devils now take on an Arsenal side which has lost just one of their last 10 Premier League matches – and that was away to Liverpool.
Manchester United received a welcome Champions League boost on Tuesday but their Premier League problems look set to continue at Chelsea. The Red Devils have lost five of their last seven games in this competition and are hard to fancy against the high-flying Blues in London.
United have produced plenty of drama in the Champions League but now have the chance to qualify for the last 16 with a match to spare as they head to Spain. Victory over Villarreal would see them reach the knockout stage and a draw will be enough if the other match in the group is also a stalemate.
Chelsea only need a point to reach the last 16 of the Champions League but will hope for more when they host Juventus. The Italian side are already guaranteed a place in the knockout stage and that can play into the hands of the Londoners.
Only a point separates these two European powerhouses in Group A and it is highly likely that this contest in Manchester will decide who finishes in top spot. Despite two talented squads on display, both clubs are still waiting to collect their first trophy in Europe’s premier club competition.
Liverpool have already qualified for the knockout stage of the Champions League as group winners so Jurgen Klopp can afford to rest some players on Wednesday. Porto, on the other hand, are a point clear of third-placed Atletico Madrid so they have everything to play for at Anfield.
Manchester City will look to back up their derby victory when they welcome out-of-form Everton to the Etihad Stadium. City, having lost at home to Crystal Palace in their last home Premier League outing, cruised to a 2-0 win at Manchester United prior to the international break.
Antonio Conte takes charge of Tottenham for the first time at home in the Premier League when Leeds visit on Sunday. The Italian saw his side claim a goalless draw at Everton last weekend, the same day as Marcelo Bielsa’s Leeds team secured an encouraging point at home to Leicester.
Steven Gerrard is back in the Premier League but Brighton could make it a tricky return to England for the former Liverpool captain. Gerrard has been appointed as Villa’s new head coach in place of Dean Smith, who was sacked following a run of five successive defeats.
West Ham spent the international break flying high in third in the Premier League and victory at Wolves would be further proof they are genuine top-four challengers. Wolves are also in fine form, with both teams picking up 16 points from their last eight matches, so this is a tough test for the Hammers.
Arsenal have made the most of a favourable run of fixtures to climb the Premier League table but faces a much tougher test at Anfield on Saturday evening. The Gunners have won six matches during an eight-game unbeaten run and are up to fifth but they did not face a top-six team in that time.
There have already been five managerial changes in the Premier League this season but Ole Gunnar Solskjaer survived the international break and now takes his Manchester United team to struggling Watford. United have only won one of their last six games but are still firm favourites to get the better of Watford.
Burnley picked up an unexpected point at Chelsea before the international break and will look to build on that at home to Crystal Palace. We’re not reading too much into that result, though, given how dominant Chelsea were and 10th-placed Palace have been much more impressive this season.